is it safe connect 5V to NOT 5V tolerant pin ?

[Ahsanu]

hey, iam new in this forum and midibox,
i try learn build stm32 midibox core by making schematic from zero, cause its my first time using stm32 uC i little bit confuse about i/o  input voltage level, in midibox core, for example PC13 can connect to 5v and 3.3v using j19, but i look in datasheet, say that pin (pc13) is not 5v tolerant.

so is connecting 5v to not 5v tolerant is safe?

i am using stm32f103rb chip,
and here i attach schematic and datasheet screenshot

thanks for attention, sorry my bad english