If you take the casing off of your mouse, it should be set up for what you want. The encoders around the mouse are set up in a L-R and up-down configuration, and the wheels are slick, but very responsive to the touch. You could mount the case-less mouse in whatever enclosure you want, and use it through a program like Girder, or bypass some of it's internal circuits, and adapt it to MIOS. Not that I know exactly how, but it seems more than possible.