... are you shure, you want to think that far before knowing the basics of what is possible from the side of your host, the protocol, the hardware etc.? Your 1056 DOUTs should be spread over 6 physical MIDI Inputs (6x8x22) of your host. I don't know nuendo good enough but I'm pretty shure it works like all other Mackie protocol based systems and it's also implemented that way from Mackie itself. - 8 faders per physical MIDI I/O. My suggestion: Think big... yes, I'm doing this too but don't expect it to be an easy way. Sometimes there are small steps and intermissions necessary to keep on track for the big plan. Greets, Roger